Before you take SIGNIFOR, tell your doctor if you:
- Have or have had high blood sugar (hyperglycemia)
- Have diabetes
- Have or have had heart problems
- Have a history of low levels of potassium or magnesium in your blood
- Have or have had liver problems
- Have or have had gallstones
- Have any other medical conditions
- Are pregnant or plan to become pregnant. SIGNIFOR may harm your unborn baby
- Are breastfeeding or plan to breastfeed. It is not known if SIGNIFOR passes into your breast milk. You and your doctor should decide if you will take SIGNIFOR or breastfeed. You should not do both
Treatment with SIGNIFOR may result in improved fertility and the possibility of unplanned pregnancy in women who have Cushing’s disease and have not gone through menopause. Talk to your healthcare provider about birth control methods that may be right for you during treatment with SIGNIFOR.
Tell a healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
SIGNIFOR and other medicines may affect each other, causing side effects. SIGNIFOR may affect the way other medicines work, and other medicines may affect how SIGNIFOR works. Your healthcare provider may need to change your dose of SIGNIFOR or your other medicines. Especially tell your healthcare provider if you take:
- Medicines to control your heartbeat (anti-arrhythmics)
- Medicines that can affect the electrical system of your heart (QT prolongation)
- Medicines to control your blood pressure (such as beta-blockers or calcium channel blockers)
- Medicines to control the electrolyte (such as potassium or magnesium) levels in your blood
Ask your healthcare provider for a list of these medicines if you are not sure.
Know the medicines you take, and keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.